Suitable for both corporate and leisure travellers, the new address is located between Tokyo Disneyland and the central districts of Marunouchi and Ginza.
The property features 105 rooms, a 24-hour business centre and a signature restaurant.
Olivier Berrivin, managing director, international operations, Asia, Best Western, commented, "With international visitor arrivals to Japan expected to soar to 40 million by the end of the decade, and Tokyo hosting the 2019 Rugby World Cup and 2020 Summer Olympics, the country is on the verge of an unprecedented tourism boom."